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KMID : 0381119800020010041
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Genes and Genomics
1980 Volume.2 No. 1 p.41 ~ p.49
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GENETIC EFFECTS OF DNA INTERCALATING AGENT, ETHIDIUM BROMIDE
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白炯錫/BAIK, HYUNG SUK
朴贊圭/河智鴻/李世永/PARK, CHAN KYU/HA, JI HONG/LEE, SE YONG
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Abstract
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The genetic effects of ethidium bromide on Salmonella typhimurium and Aspergillus
nidulans were studied.
Ethidium bromide was only weakly mutagenic on Salmonella typhimurium directly but
upon the activation by the rat liver micre-somal enzymes became highly mutagenic on
the frameshift mutant of Salmonella typhimurium.
Ethidium bromide was not mutagenic on Aspergillus nidulans directly or with the rat
liver microsomal enzymes. However, it induced mitotic recombinations in the fungi in
high frequencies.
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KEYWORD
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